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IHS_EWBIEEE xploreSTRATEGY ANALYTICSIHS_EWB_GF

Protein Purification & Isolation Market by Technology by Product by Application & End User - Global Forecast to 2020

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出 版 商:MarketsandMarkets
出版日期:2015/05/06
頁  數:251頁
文件格式:PDF
價  格:
USD 4,650 (Single-User License)
USD 5,650 (Multi-User License)
USD 9,000 (Global-User License)
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 Protein purification involves the process of isolating proteins from the source, based on differences in their physical properties. The objective of a protein purification process is to isolate the largest amount of functional protein with fewest contaminants. The global protein purification and isolation market is expected to grow at a CAGR of around 5% to 6% during the forecast period. This market is mainly driven by increased research in the pharmaceutical and biotechnological fields, growing need to identify new protein-based drug molecules, and growing demand for rapid purification kits to rapidly screen, prepare, purify, and concentrate protein samples. In addition, various factors, such as increased funding from both public and private research bodies for research and development; growing research in the field of structure-based drug design; and technological innovations in protein purification and isolation technologies are offering significant growth opportunities for the market. However, high cost of purification instruments, soaring research and development cost, and dearth of skilled professionals are restricting the growth of this market to a certain extent.
The global protein purification and isolation market is broadly segmented by technology, product, application, and end user. By technology, the protein purification and isolation market is segmented into ultrafiltration, precipitation, preparative chromatography techniques, electrophoresis, Western blotting, dialysis and diafiltration, and centrifugation. By product, the market is segmented into instruments and consumables. On the basis of applications, the market is segmented into drug screening, protein-protein interaction studies, biomarker discovery, target identification, protein therapeutics, and disease diagnostics and monitoring. On the basis of end users, the market is segmented into academic medical institutes, hospitals and diagnostics centers, pharmaceutical and biotechnology companies, and contract research organizations.
In 2014, North America accounted for the largest share of the protein purification and isolation market, followed by Europe, Asia-Pacific, and RoW. This region will continue to dominate the market during the forecast period; however, Asia-Pacific is expected to witness the fastest growth rate during the forecast period, largely driven by growing investments in emerging countries such as China, India, and Brazil for the protein purification and isolation sector. 
The global protein purification and isolation market is consolidated in nature, with major players such as Thermo Fisher Scientific, Inc. (U.S.), Merck Millipore (U.S.), QIAGEN N.V. (Netherlands), Bio-Rad Laboratories, Inc. (U.S.), and Agilent Technologies (U.S.). The other market players include Sigma-Aldrich Corporation (U.S.), Promega Corporation (U.S.), Purolite Corporation (U.S.), GE Healthcare Life Sciences (U.K.), and Roche Applied Science (Switzerland).
Reasons to Buy the Report 
The report will enrich both established firms as well as new entrants/smaller firms to gauge the pulse of the market which in turn will help the firms in garnering a greater market share. Firms purchasing the report could use any one or combination of the below-mentioned five strategies (market penetration, product development/innovation, market development, market diversification, and competitive assessment) for reaping a greater market share.
This report provides insights on the following pointers:
• Market Penetration: Comprehensive information on product portfolios offered by the top players in the protein purification and isolation market. The report analyzes the protein purification and isolation market by product, technology, application, and end user, across all regions
• Product Development/Innovation: Detailed insights on the upcoming trends, research and development activities, and new product launches in the protein purification and isolation market
• Market Development: Comprehensive information about the lucrative emerging markets by product, technology, application, end user, and geography
• Market Diversification: Exhaustive information of new products, growing regions, recent developments, and investments in the protein purification and isolation market
• Competitive Assessment: In-depth assessment of market shares, growth strategies, products, distribution networks, manufacturing capabilities, and SWOT analysis of the leading players in the protein purification and isolation market
 TABLE OF CONTENTS
1 INTRODUCTION 18
1.1 OBJECTIVES OF THE STUDY 18
1.2 MARKET DEFINITION 18
1.3 MARKET SCOPE 19
1.3.1 MARKETS COVERED 19
1.3.2 YEARS CONSIDERED FOR THE STUDY 21
1.4 CURRENCY 22
1.5 STAKEHOLDERS 22
2 RESEARCH METHODOLOGY 23
2.1 RESEARCH APPROACH 23
2.1.1 SECONDARY DATA 24
2.1.1.1 Key data from secondary sources 24
2.1.2 PRIMARY DATA 25
2.1.2.1 key data from primary sources 25
2.1.2.2 Key industry insights 26
2.2 MARKET SIZE ESTIMATION 27
2.3 MARKET BREAKDOWN AND DATA TRIANGULATION 28
2.4 MARKET SHARE ESTIMATION 30
2.5 RESEARCH ASSUMPTIONS 30
2.5.1 ASSUMPTIONS FOR THE STUDY 30
3 EXECUTIVE SUMMARY 31
3.1 INTRODUCTION 31
4 PREMIUM INSIGHTS 36
4.1 GROWTH POTENTIAL OF THE PROTEIN PURIFICATION AND ISOLATION MARKET 36
4.2 ASIA-PACIFIC: PROTEIN PURIFICATION AND ISOLATION MARKET, BY PRODUCT (2014) 37
4.3 PROTEIN PURIFICATION AND ISOLATION MARKET: REGIONAL GROWTH OPPORTUNITIES 38
4.4 PROTEIN PURIFICATION AND ISOLATION MARKET, REGIONAL MIX 39
4.5 PROTEIN PURIFICATION AND ISOLATION MARKET: DEVELOPED VS. DEVELOPING COUNTRIES/REGION 40
5 MARKET OVERVIEW 41
5.1 INTRODUCTION 42
5.2 MARKET SEGMENTATION 42
5.2.1 BY PRODUCT 42
5.2.2 BY TECHNOLOGY 43
5.2.3 BY APPLICATION 43
5.2.4 BY END USER 43
5.3 MARKET DYNAMICS 44
5.4 KEY MARKET DRIVERS 45
5.4.1 GROWING ADOPTION OF AUTOMATED PURIFICATION INSTRUMENTS 45
5.4.2 EXTENSIVE PROTEOMICS RESEARCH 45
5.4.3 INCREASING R&D EXPENDITURE IN PHARMACEUTICAL AND BIOTECHNOLOGICAL COMPANIES 46
5.4.4 HIGH DEMAND FOR PROTEIN BIOLOGICS 46
5.5 KEY MARKET RESTRAINTS 48
5.5.1 LOW PENETRATION OF AUTOMATED PROTEIN PURIFICATION INSTRUMENTS IN EMERGING ECONOMIES 48
5.5.2 NEED FOR HIGHLY QUALIFIED RESEARCHERS & MANDATORY TRAINING INCREASES COST OF DOWNSTREAM PROCESS 48
5.6 KEY MARKET OPPORTUNITIES 49
5.6.1 GROWING NEED TO IDENTIFY NEW LIGANDS FOR THE DRUG DISCOVERY PROCESS 49
5.6.2 INCREASING DEMAND FOR PROTEIN THERAPEUTICS 49
5.7 KEY CHALLENGE 50
5.7.1 DEVELOPMENT OF HIGH-THROUGHPUT PLATFORMS FOR THE EXPRESSION AND PURIFICATION OF MEMBRANE PROTEINS 50
6 INDUSTRY INSIGHTS 52
6.1 INTRODUCTION 52
6.2 INDUSTRY TRENDS 52
6.2.1 SINGLE-USE TECHNOLOGY 53
6.2.2 PROTEIN PURIFICATION USING TWIN-COLUMN, COUNTERCURRENT CHROMATOGRAPHIC CAPTURE TECHNOLOGY 53
6.3 PORTER’S FIVE FORCES ANALYSIS 54
6.3.1 THREAT OF NEW ENTRANTS 54
6.3.2 THREAT OF SUBSTITUTES 55
6.3.3 BARGAINING POWER OF SUPPLIERS 55
6.3.4 BARGAINING POWER OF BUYERS 56
6.3.5 INTENSITY OF COMPETITIVE RIVALRY 56
6.4 STRATEGIC BENCHMARKING 57
6.4.1 CHANGING END-USER DEMANDS AT THE FOCUS OF INNOVATION FROM LEADING PLAYERS IN THE MARKET 57
7 GLOBAL PROTEIN PURIFICATION AND ISOLATION MARKET, BY PRODUCT 59
7.1 INTRODUCTION 60
7.2 INSTRUMENTS 62
7.3 CONSUMABLES 64
7.3.1 PROTEIN PURIFICATION KITS 65
7.3.2 PROTEIN PURIFICATION REAGENTS 66
7.3.3 PREPACKED COLUMNS 68
7.3.4 PROTEIN PURIFICATION RESINS 69
7.3.5 MAGNETIC BEADS 70
7.3.6 OTHER CONSUMABLES 72
8 GLOBAL PROTEIN PURIFICATION AND ISOLATION MARKET, BY TECHNOLOGY 73
8.1 INTRODUCTION 74
8.2 ULTRAFILTRATION 76
8.3 PRECIPITATION 78
8.4 PREPARATIVE CHROMATOGRAPHY 79
8.4.1 AFFINITY CHROMATOGRAPHY 81
8.4.1.1 Immobilized metal ion affinity chromatography (IMAC) 83
8.4.1.2 Immunoaffinity chromatography (IAC) 84
8.4.1.3 Bead-based chromatography 85
8.4.2 ION EXCHANGE CHROMATOGRAPHY (IEXC) 86
8.4.3 REVERSE-PHASE CHROMATOGRAPHY (RPC) 88
8.4.4 HYDROPHOBIC CHARGE INDUCTION CHROMATOGRAPHY (HCIC) 89
8.4.5 SIZE EXCLUSION CHROMATOGRAPHY (GEL FILTRATION) 90
8.5 ELECTROPHORESIS 91
8.5.1 GEL ELECTROPHORESIS 92
8.5.2 ISOELECTRIC FOCUSING 93
8.5.3 CAPILLARY ELECTROPHORESIS 94
8.6 WESTERN BLOTTING (IMMUNOBLOTTING) 96
8.7 DIALYSIS AND DIAFILTRATION 97
8.8 CENTRIFUGATION 98
9 GLOBAL PROTEIN PURIFICATION AND ISOLATION MARKET, BY APPLICATION 100
9.1 INTRODUCTION 101
9.2 DRUG SCREENING 102
9.3 PROTEIN-PROTEIN INTERACTION STUDIES 104
9.4 BIOMARKER DISCOVERY 106
9.5 TARGET IDENTIFICATION 108
9.6 PROTEIN THERAPEUTICS 109
9.7 DISEASE DIAGNOSTICS AND MONITORING 111
10 GLOBAL PROTEIN PURIFICATION AND ISOLATION MARKET, BY END USER 113
10.1 INTRODUCTION 114
10.2 ACADEMIC RESEARCH INSTITUTIONS 115
10.3 HOSPITALS AND DIAGNOSTIC CENTERS 117
10.4 PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES 119
10.5 CONTRACT RESEARCH ORGANIZATIONS 120
11 GLOBAL PROTEIN PURIFICATION AND ISOLATION MARKET, BY REGION 122
11.1 INTRODUCTION 123
11.2 NORTH AMERICA 126
11.2.1 U.S. 130
11.2.2 CANADA 134
11.3 EUROPE 138
11.3.1 GERMANY 142
11.3.2 U.K. 145
11.3.3 FRANCE 148
11.3.4 ITALY 151
11.3.5 SPAIN 154
11.3.6 ROE 157
11.4 ASIA-PACIFIC 161
11.4.1 JAPAN 166
11.4.2 INDIA 170
11.4.3 CHINA 173
11.4.4 REST OF ASIA-PACIFIC(ROAPAC) 176
11.5 REST OF THE WORLD (ROW) 180
11.5.1 LATIN AMERICA 183
11.5.2 MIDDLE EAST AND AFRICA 186
12 COMPETITIVE LANDSCAPE 190
12.1 OVERVIEW 190
12.2 MARKET SHARE ANALYSIS 191
12.3 COMPETITIVE SITUATION AND TRENDS 193
12.3.1 NEW PRODUCT LAUNCHES 194
12.3.2 EXPANSIONS 195
12.3.3 MERGERS AND ACQUISITIONS 196
12.3.4 AGREEMENTS AND COLLABORATIONS 197
13 COMPANY PROFILES 199
(Overview, Financials, Products & Services, Strategy, & Developments)*
13.1 INTRODUCTION 199
13.2 THERMO FISHER SCIENTIFIC, INC. 200
13.3 SIGMA-ALDRICH CORPORATION 208
13.4 QIAGEN N.V. 212
13.5 GENERAL ELECTRIC COMPANY 215
13.6 MERCK MILLIPORE 220
13.7 AGILENT TECHNOLOGIES, INC. 224
13.8 BIO-RAD LABORATORIES, INC. 228
13.9 PROMEGA CORPORATION 233
13.10 PUROLITE CORPORATION 236
13.11 ROCHE DIAGNOSTICS (DIVISION OF F. HOFFMANN-LA ROCHE LTD.) 238
*Details on Financials, Product & Services, Strategy, & Developments might not be captured in case of unlisted companies.
14 APPENDIX 241
14.1 INSIGHTS OF INDUSTRY EXPERTS 241
14.2 DISCUSSION GUIDE 242
14.3 OTHER DEVELOPMENTS, 2011–2015 247
14.4 INTRODUCING RT: REAL-TIME MARKET INTELLIGENCE 248
14.5 AVAILABLE CUSTOMIZATIONS 249
14.6 RELATED REPORTS 250
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